Neutrophil-to-lymphocyte ratio in head and neck cancer

Neutrophil-to-lymphocyte ratio in head and neck cancer

Introduction The neutrophil‐to‐lymphocyte ratio (NLR) is an index of systemic inflammatory burden in malignancy. An elevated NLR has been associated with poor prognosis in a number of cancer sites. We investigated its role in a cohort of patients with locally advanced head and neck cancer. Methods E...

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Veröffentlicht in:Journal of medical imaging and radiation oncology 2015-08, Vol.59 (4), p.514-519
Hauptverfasser: Haddad, Carol R, Guo, Linxin, Clarke, Stephen, Guminski, Alex, Back, Michael, Eade, Thomas
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Biomarkers - blood
Carcinoma, Squamous Cell - blood
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Disease-Free Survival
Female
Head & neck cancer
head and neck cancer
Head and Neck Neoplasms - blood
Head and Neck Neoplasms - mortality
Head and Neck Neoplasms - pathology
Humans
inflammation
Leukocyte Count - statistics & numerical data
Lymphocytes - pathology
Male
Medical prognosis
Metastasis
Middle Aged
neutrophil-to-lymphocyte ratio
Neutrophils - pathology
New South Wales - epidemiology
NLR
Prevalence
radiotherapy
Reproducibility of Results
Risk Factors
Sensitivity and Specificity
Survival Rate
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Zusammenfassung:Introduction The neutrophil‐to‐lymphocyte ratio (NLR) is an index of systemic inflammatory burden in malignancy. An elevated NLR has been associated with poor prognosis in a number of cancer sites. We investigated its role in a cohort of patients with locally advanced head and neck cancer. Methods Eligible patients had primary mucosal squamous cell carcinoma treated with chemoradiotherapy and a minimum follow‐up of 12 months (unless deceased). NLR was analysed as
ISSN:1754-9477
1754-9485
DOI:10.1111/1754-9485.12305