Hypersensitivity Hepatitis due to Pyrazinamide
Pyrazinamide hepatotoxicity is considered secondary to a direct and dose-related toxic effect. At currently used doses, pyrazinamide provides effective short-term treatment and is free from serious side effects. We report a case of pyrazinamide-induced hepatitis for which the rechallenge data strong...
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| Veröffentlicht in: | Scandinavian journal of infectious diseases 1995, Vol.27 (1), p.93-94 |
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| container_end_page | 94 |
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| container_issue | 1 |
| container_start_page | 93 |
| container_title | Scandinavian journal of infectious diseases |
| container_volume | 27 |
| creator | Corbella, Xavier Vadillo, Miquel Cabellos, Carmen Fernandezviladrich, Pedro Rufi, Gabriel |
| description | Pyrazinamide hepatotoxicity is considered secondary to a direct and dose-related toxic effect. At currently used doses, pyrazinamide provides effective short-term treatment and is free from serious side effects. We report a case of pyrazinamide-induced hepatitis for which the rechallenge data strongly suggest a hypersensitivity mechanism. |
| doi_str_mv | 10.3109/00365549509018984 |
| format | Article |
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At currently used doses, pyrazinamide provides effective short-term treatment and is free from serious side effects. We report a case of pyrazinamide-induced hepatitis for which the rechallenge data strongly suggest a hypersensitivity mechanism.</description><subject>Acute Disease</subject><subject>Biological and medical sciences</subject><subject>Chemical and Drug Induced Liver Injury - etiology</subject><subject>Chemical and Drug Induced Liver Injury - immunology</subject><subject>Dose-Response Relationship, Drug</subject><subject>Drug Hypersensitivity</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Female</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. 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Drug treatments</topic><topic>Pyrazinamide - adverse effects</topic><topic>Toxicity: digestive system</topic><toplevel>online_resources</toplevel><creatorcontrib>Corbella, Xavier</creatorcontrib><creatorcontrib>Vadillo, Miquel</creatorcontrib><creatorcontrib>Cabellos, Carmen</creatorcontrib><creatorcontrib>Fernandezviladrich, Pedro</creatorcontrib><creatorcontrib>Rufi, Gabriel</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Scandinavian journal of infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Corbella, Xavier</au><au>Vadillo, Miquel</au><au>Cabellos, Carmen</au><au>Fernandezviladrich, Pedro</au><au>Rufi, Gabriel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hypersensitivity Hepatitis due to Pyrazinamide</atitle><jtitle>Scandinavian journal of infectious diseases</jtitle><addtitle>Scand J Infect Dis</addtitle><date>1995</date><risdate>1995</risdate><volume>27</volume><issue>1</issue><spage>93</spage><epage>94</epage><pages>93-94</pages><issn>0036-5548</issn><eissn>1651-1980</eissn><coden>SJIDB7</coden><abstract>Pyrazinamide hepatotoxicity is considered secondary to a direct and dose-related toxic effect. 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| fulltext | fulltext |
| identifier | ISSN: 0036-5548 |
| ispartof | Scandinavian journal of infectious diseases, 1995, Vol.27 (1), p.93-94 |
| issn | 0036-5548 1651-1980 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_16991107 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Acute Disease Biological and medical sciences Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - immunology Dose-Response Relationship, Drug Drug Hypersensitivity Drug toxicity and drugs side effects treatment Female Humans Medical sciences Middle Aged Pharmacology. Drug treatments Pyrazinamide - adverse effects Toxicity: digestive system |
| title | Hypersensitivity Hepatitis due to Pyrazinamide |
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