Carotid plaque elasticity estimation using ultrasound elastography, MRI, and inverse FEA – A numerical feasibility study

Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be...

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Veröffentlicht in:Medical engineering & physics 2015-08, Vol.37 (8), p.801-807
Hauptverfasser: Nieuwstadt, H.A, Fekkes, S, Hansen, H.H.G, de Korte, C.L, van der Lugt, A, Wentzel, J.J, van der Steen, A.F.W, Gijsen, F.J.H
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container_end_page 807
container_issue 8
container_start_page 801
container_title Medical engineering & physics
container_volume 37
creator Nieuwstadt, H.A
Fekkes, S
Hansen, H.H.G
de Korte, C.L
van der Lugt, A
Wentzel, J.J
van der Steen, A.F.W
Gijsen, F.J.H
description Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be to apply our method in vivo.
doi_str_mv 10.1016/j.medengphy.2015.06.003
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source MEDLINE; Elsevier ScienceDirect Journals
subjects Biomechanical modeling
Carotid Artery Diseases - diagnostic imaging
Carotid Artery Diseases - pathology
Carotid atherosclerosis
Computer Simulation
Elasticity estimation
Elasticity Imaging Techniques - methods
Feasibility Studies
Finite Element Analysis
Humans
Inverse problem
Magnetic resonance imaging
Magnetic Resonance Imaging - methods
Models, Cardiovascular
Nonlinear Dynamics
Plaque, Atherosclerotic - diagnostic imaging
Plaque, Atherosclerotic - pathology
Radiology
Ultrasound elastography
title Carotid plaque elasticity estimation using ultrasound elastography, MRI, and inverse FEA – A numerical feasibility study
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