Carotid plaque elasticity estimation using ultrasound elastography, MRI, and inverse FEA – A numerical feasibility study

Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be...

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Veröffentlicht in:	Medical engineering & physics 2015-08, Vol.37 (8), p.801-807
Hauptverfasser:	Nieuwstadt, H.A, Fekkes, S, Hansen, H.H.G, de Korte, C.L, van der Lugt, A, Wentzel, J.J, van der Steen, A.F.W, Gijsen, F.J.H
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomechanical modeling Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - pathology Carotid atherosclerosis Computer Simulation Elasticity estimation Elasticity Imaging Techniques - methods Feasibility Studies Finite Element Analysis Humans Inverse problem Magnetic resonance imaging Magnetic Resonance Imaging - methods Models, Cardiovascular Nonlinear Dynamics Plaque, Atherosclerotic - diagnostic imaging Plaque, Atherosclerotic - pathology Radiology Ultrasound elastography
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Beschreibung
Zusammenfassung:	Highlights • We introduce a method to noninvasively determine plaque material properties. • MRI is used to obtain the geometry, US to obtain strains, and FEA to combine them. • Our numerical simulation-approach shows that our method is feasible. • Due to our positive findings, the next step would be to apply our method in vivo.
ISSN:	1350-4533 1873-4030
DOI:	10.1016/j.medengphy.2015.06.003