Gaseous mediators in resolution of inflammation
Highlights • There are many gaseous signaling molecules, but the best characterized are nitric oxide, hydrogen sulfide and carbon monoxide. • These gasotransmitters have potent anti-inflammatory effects and can promote resolution of inflammation and wound healing. • Novel anti-inflammatory therapeut...
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| Veröffentlicht in: | Seminars in immunology 2015-05, Vol.27 (3), p.227-233 |
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| container_title | Seminars in immunology |
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| creator | Wallace, John L Ianaro, Angela Flannigan, Kyle L Cirino, Giuseppe |
| description | Highlights • There are many gaseous signaling molecules, but the best characterized are nitric oxide, hydrogen sulfide and carbon monoxide. • These gasotransmitters have potent anti-inflammatory effects and can promote resolution of inflammation and wound healing. • Novel anti-inflammatory therapeutics are in development which exploit the powerful anti-inflammatory effects of one or more of these gaseous mediators. |
| doi_str_mv | 10.1016/j.smim.2015.05.004 |
| format | Article |
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| ispartof | Seminars in immunology, 2015-05, Vol.27 (3), p.227-233 |
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| source | MEDLINE; ScienceDirect Journals (5 years ago - present) |
| subjects | Allergy and Immunology Anti-inflammatory Anti-Inflammatory Agents - therapeutic use Apoptosis - drug effects Carbon monoxide Carbon Monoxide - therapeutic use Cytoprotection Cytoprotection - drug effects Gasotransmitters - metabolism Homeostasis - drug effects Homeostasis - immunology Humans Hydrogen sulfide Hydrogen Sulfide - therapeutic use Inflammation - drug therapy Inflammation - immunology Inflammation - pathology Nitric oxide Nitric Oxide - therapeutic use Signal Transduction - drug effects Signal Transduction - immunology |
| title | Gaseous mediators in resolution of inflammation |
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