Gender specific association of decreased bone mineral density in patients with epilepsy

Gender specific association of decreased bone mineral density in patients with epilepsy

To evaluate whether epilepsy or certain antiepileptic drugs render patients prone to develop low bone mineral density (BMD) and osteoporosis risk. Thirty-eight (27 males, 11 females) consecutive adult epileptic patients receiving antiepileptic drugs (AEDs) and 71 control individuals matched for race...

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Veröffentlicht in:Neurologia i neurochirurgia polska 2015-01, Vol.49 (4), p.267-271
Hauptverfasser: Markoula, Sofia, Sioka, Chrissa, Exarchopoulos, Thomas, Chatzistefanidis, Dimitrios, Kalef-Ezra, John, Fotopoulos, Andreas, Kyritsis, Athanassios P.
Format: Artikel
Sprache:eng
Schlagworte:
Absorptiometry, Photon
Adult
Anticonvulsants - adverse effects
Antiepileptic drugs
Bone Density
Bone mineral density
Epilepsy
Epilepsy - complications
Epilepsy - drug therapy
Female
Humans
Male
Males
Middle Aged
Osteoporosis
Osteoporosis - chemically induced
Osteoporosis - etiology
Sex Factors
X-ray absorptiometry
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Zusammenfassung:To evaluate whether epilepsy or certain antiepileptic drugs render patients prone to develop low bone mineral density (BMD) and osteoporosis risk. Thirty-eight (27 males, 11 females) consecutive adult epileptic patients receiving antiepileptic drugs (AEDs) and 71 control individuals matched for race, gender, age and body mass index (BMI) were subjected to dual energy X-ray absorptiometry (DXA). The mean lumbar spine and total hip BMD values were lower in the patients compared to control group (0.90±0.24g/cm2 vs 1.04±0.14g/cm2, p
ISSN:0028-3843
1897-4260
DOI:10.1016/j.pjnns.2015.06.007