Ectosomes and exosomes: shedding the confusion between extracellular vesicles
Highlights • The characteristics and mechanisms of ectosomes and exosomes are defined. • Exosomes are released on the exocytosis of MVBs, whereas ectosomes are assembled and released from the plasma membrane. • Interactions of vesicles with target cells and vesicle navigation are illustrated. • The...
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| Veröffentlicht in: | Trends in cell biology 2015-06, Vol.25 (6), p.364-372 |
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| container_end_page | 372 |
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| container_title | Trends in cell biology |
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| creator | Cocucci, Emanuele Meldolesi, Jacopo |
| description | Highlights • The characteristics and mechanisms of ectosomes and exosomes are defined. • Exosomes are released on the exocytosis of MVBs, whereas ectosomes are assembled and released from the plasma membrane. • Interactions of vesicles with target cells and vesicle navigation are illustrated. • The role of vesicles in cancer diagnosis and therapy is discussed. |
| doi_str_mv | 10.1016/j.tcb.2015.01.004 |
| format | Article |
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| ispartof | Trends in cell biology, 2015-06, Vol.25 (6), p.364-372 |
| issn | 0962-8924 1879-3088 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Animals cancer diagnosis and therapy Cell Communication - physiology cell targets Cell-Derived Microparticles - metabolism endocytosis ESCRT Exocytosis - physiology Exosomes - metabolism extracellular vesicles Humans membrane fusions mediated by fusogens multivesicular bodies Multivesicular Bodies - metabolism Pathology vesicle assembly vesicle pinching off and release |
| title | Ectosomes and exosomes: shedding the confusion between extracellular vesicles |
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