Harnessing magnetic-mechano actuation in regenerative medicine and tissue engineering

Highlights • Magnetic actuation is a valuable toolbox to remotely guide, engraft, and differentiate stem cells. • Magnetic-assisted tissue engineering makes possible the fabrication of tissue grafts scaffold-free from mesenchymal and induced pluripotent stem cells. • Combination of magnetic material...

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Veröffentlicht in:	Trends in biotechnology (Regular ed.) 2015-08, Vol.33 (8), p.471-479
Hauptverfasser:	Santos, Lívia J, Reis, Rui L, Gomes, Manuela E
Format:	Artikel
Sprache:	eng
Schlagworte:	activation of mechanotransduction signalling pathways Aging Animals Biomaterials Biomedical materials Blood pressure Cell differentiation Cell division Genotype & phenotype Homeostasis Humans Hydroxyapatite Hypertension Internal Medicine Kinases magnetic biomaterials magnetic-based cell manipulation Magnetics mechanosensing machinery Mechanotransduction, Cellular - physiology Medicine Mice Osteoporosis Physiology Proteins regenerative medicine Regenerative Medicine - methods Stem cells Tissue engineering Tissue Engineering - methods Topography Transcription factors
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Beschreibung
Zusammenfassung:	Highlights • Magnetic actuation is a valuable toolbox to remotely guide, engraft, and differentiate stem cells. • Magnetic-assisted tissue engineering makes possible the fabrication of tissue grafts scaffold-free from mesenchymal and induced pluripotent stem cells. • Combination of magnetic materials and magnetic force is a promising platform for the delivery of drugs and cells on demand.
ISSN:	0167-7799 1879-3096
DOI:	10.1016/j.tibtech.2015.06.006