Association of restless legs syndrome with oxidative stress and inflammation in patients undergoing hemodialysis

Highlights • Restless legs syndrome is a common comorbidity in patients undergoing hemodialysis. • Restless legs syndrome was associated with oxidative stress and inflammation. • Serum 8-OHdG level was a significant independent predictor of RLS severity.

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Bibliographische Detailangaben
Veröffentlicht in:	Sleep medicine 2015-08, Vol.16 (8), p.941-948
Hauptverfasser:	Higuchi, Terumi, Abe, Masanori, Mizuno, Mari, Yamazaki, Toshio, Suzuki, Hiroko, Moriuchi, Masari, Oikawa, Osamu, Okawa, Erina, Ando, Hideyuki, Okada, Kazuyoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	8-Hydroxy-2′-deoxyguanosine Adult Aged Aged, 80 and over Cross-Sectional Studies Deoxyguanosine - analogs & derivatives Deoxyguanosine - blood Female Hemodialysis Humans Inflammation - etiology Inflammation - physiopathology Male Middle Aged N-terminal pro-B-type natriuretic peptide Neurology Oxidative Stress Prevalence Renal Dialysis - adverse effects Restless legs syndrome Restless Legs Syndrome - epidemiology Restless Legs Syndrome - etiology Restless Legs Syndrome - physiopathology Risk Factors Severity of Illness Index Sleep Medicine
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Beschreibung
Zusammenfassung:	Highlights • Restless legs syndrome is a common comorbidity in patients undergoing hemodialysis. • Restless legs syndrome was associated with oxidative stress and inflammation. • Serum 8-OHdG level was a significant independent predictor of RLS severity.
ISSN:	1389-9457 1878-5506
DOI:	10.1016/j.sleep.2015.03.025