Adrenal function and microbial DNA in noninfected cirrhotic patients with ascites: Relationship and effect on survival

Adrenal function and microbial DNA in noninfected cirrhotic patients with ascites: Relationship and effect on survival

Abstract Background There are few data on clinical relevance of adrenal dysfunction and its relationship with occult microbial DNA in noninfected haemodynamically stable cirrhotic patients with ascites. Aims The aim of this study was to evaluate prognostic role of adrenal dysfunction, microbial DNA,...

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Veröffentlicht in:Digestive and liver disease 2015-08, Vol.47 (8), p.702-708
Hauptverfasser: Risso, Alessandro, Alessandria, Carlo, Mezzabotta, Lavinia, Elia, Chiara, Andrealli, Alida, Spandre, Maurizio, Di Luigi, Paola, Barbui, Anna, Evangelista, Andrea, Morgando, Anna, Serra, Roberto, Ciccone, Giovannino, Marzano, Alfredo, Rizzetto, Mario
Format: Artikel
Sprache:eng
Schlagworte:
Adrenal insufficiency
Adrenal Insufficiency - blood
Adrenal Insufficiency - complications
Aged
Ascites
Ascites - etiology
Ascites - metabolism
Ascites - microbiology
Bacterial DNA
Cirrhosis
DNA, Bacterial - blood
DNA, Bacterial - metabolism
DNA, Fungal - blood
DNA, Fungal - metabolism
End Stage Liver Disease - blood
End Stage Liver Disease - etiology
Female
Gastroenterology and Hepatology
Humans
Hydrocortisone - blood
Liver Cirrhosis - blood
Liver Cirrhosis - complications
Liver Cirrhosis - mortality
Liver Transplantation
Male
Middle Aged
Survival Rate
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Zusammenfassung:Abstract Background There are few data on clinical relevance of adrenal dysfunction and its relationship with occult microbial DNA in noninfected haemodynamically stable cirrhotic patients with ascites. Aims The aim of this study was to evaluate prognostic role of adrenal dysfunction, microbial DNA, and their relationship. Methods Adrenal function was assessed in 93 consecutive patients following a corticotropin stimulation test. Adrenal dysfunction was defined as: basal cortisol
ISSN:1590-8658
1878-3562
DOI:10.1016/j.dld.2015.04.010