Fatal Group A Streptococcal Meningitis and Toxic Shock-Like Syndrome: Case Report
A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a va...
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| Veröffentlicht in: | Clinical infectious diseases 1994-01, Vol.18 (1), p.91-93 |
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| container_end_page | 93 |
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| container_issue | 1 |
| container_start_page | 91 |
| container_title | Clinical infectious diseases |
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| creator | Jevon, Gareth P. Dunne, W. Michael Hawkins, Hal K. Armstrong, Dawna L. Musser, James M. |
| description | A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome. |
| doi_str_mv | 10.1093/clinids/18.1.91 |
| format | Article |
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Michael</creatorcontrib><creatorcontrib>Hawkins, Hal K.</creatorcontrib><creatorcontrib>Armstrong, Dawna L.</creatorcontrib><creatorcontrib>Musser, James M.</creatorcontrib><title>Fatal Group A Streptococcal Meningitis and Toxic Shock-Like Syndrome: Case Report</title><title>Clinical infectious diseases</title><addtitle>Clinical Infectious Diseases</addtitle><description>A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. 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Michael ; Hawkins, Hal K. ; Armstrong, Dawna L. ; Musser, James M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c477t-f92dcf3148bec4f326710fc34e268c3f194a172e77437b25535ad84d2877f5923</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1994</creationdate><topic>Bacterial diseases</topic><topic>Biological and medical sciences</topic><topic>Brain - microbiology</topic><topic>Brain - pathology</topic><topic>Chickenpox</topic><topic>Child</topic><topic>Exanthema</topic><topic>Exotoxins</topic><topic>Fatal Outcome</topic><topic>Female</topic><topic>Gram positive cocci</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Meningitis</topic><topic>Meningitis, Bacterial - cerebrospinal fluid</topic><topic>Meningitis, Bacterial - microbiology</topic><topic>Meningitis, Bacterial - pathology</topic><topic>Nervous system diseases</topic><topic>Pathology</topic><topic>Shock, Septic - cerebrospinal fluid</topic><topic>Shock, Septic - microbiology</topic><topic>Staphylococcal infections, streptococcal infections, pneumococcal infections</topic><topic>Streptococcal Infections - cerebrospinal fluid</topic><topic>Streptococcal Infections - pathology</topic><topic>Streptococcus pyogenes</topic><topic>Toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Jevon, Gareth P.</creatorcontrib><creatorcontrib>Dunne, W. Michael</creatorcontrib><creatorcontrib>Hawkins, Hal K.</creatorcontrib><creatorcontrib>Armstrong, Dawna L.</creatorcontrib><creatorcontrib>Musser, James M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Clinical infectious diseases</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Jevon, Gareth P.</au><au>Dunne, W. Michael</au><au>Hawkins, Hal K.</au><au>Armstrong, Dawna L.</au><au>Musser, James M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fatal Group A Streptococcal Meningitis and Toxic Shock-Like Syndrome: Case Report</atitle><jtitle>Clinical infectious diseases</jtitle><addtitle>Clinical Infectious Diseases</addtitle><date>1994-01</date><risdate>1994</risdate><volume>18</volume><issue>1</issue><spage>91</spage><epage>93</epage><pages>91-93</pages><issn>1058-4838</issn><eissn>1537-6591</eissn><coden>CIDIEL</coden><abstract>A previously healthy 8-year-old girl presented with flulike symptoms, developed toxic shock-like syndrome, and died within 48 hours. At autopsy she was found to have purulent meningitis. The group A β-hemolytic streptococcus isolated from her CSF was a member of clone ET 2. This strain produced a variant form of streptococcal pyrogenic exotoxin A (SPEA2) that has recently been associated with widespread toxic shock-like syndrome.</abstract><cop>Chicago, IL</cop><pub>The University of Chicago Press</pub><pmid>8054439</pmid><doi>10.1093/clinids/18.1.91</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1058-4838 |
| ispartof | Clinical infectious diseases, 1994-01, Vol.18 (1), p.91-93 |
| issn | 1058-4838 1537-6591 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_16977279 |
| source | MEDLINE; Oxford University Press Journals Digital Archive Legacy; JSTOR Archive Collection A-Z Listing |
| subjects | Bacterial diseases Biological and medical sciences Brain - microbiology Brain - pathology Chickenpox Child Exanthema Exotoxins Fatal Outcome Female Gram positive cocci Human bacterial diseases Humans Infections Infectious diseases Medical sciences Meningitis Meningitis, Bacterial - cerebrospinal fluid Meningitis, Bacterial - microbiology Meningitis, Bacterial - pathology Nervous system diseases Pathology Shock, Septic - cerebrospinal fluid Shock, Septic - microbiology Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcal Infections - cerebrospinal fluid Streptococcal Infections - pathology Streptococcus pyogenes Toxicity |
| title | Fatal Group A Streptococcal Meningitis and Toxic Shock-Like Syndrome: Case Report |
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