Evaluation of long term (10-years+) dysphagia and trismus in patients treated with concurrent chemo-radiotherapy for advanced head and neck cancer

Highlights • Long-term dysphagia after CRT for advanced HNC forms a substantial QoL problem. • There is a significant correlation between trismus and laryngeal aspiration. • IMRT results in less swallowing impairment and trismus than conventional RT.

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Bibliographische Detailangaben
Veröffentlicht in:	Oral oncology 2015-08, Vol.51 (8), p.787-794
Hauptverfasser:	Kraaijenga, S.A.C, Oskam, I.M, van der Molen, L, Hamming-Vrieze, O, Hilgers, F.J.M, van den Brekel, M.W.M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma, Squamous Cell - therapy Chemoradiotherapy - adverse effects Deglutition disorders Deglutition Disorders - epidemiology Deglutition Disorders - etiology Dysphagia Female Head and neck cancer Head and Neck Neoplasms - therapy Hematology, Oncology and Palliative Medicine Humans Intensity modulated radiotherapy Long-term effects Male Middle Aged Multicenter Studies as Topic Otolaryngology Quality of Life Radiation Injuries - epidemiology Radiotherapy, Intensity-Modulated - adverse effects Randomized Controlled Trials as Topic Surveys and Questionnaires Treatment Outcome Trismus Trismus - epidemiology Trismus - etiology
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Beschreibung
Zusammenfassung:	Highlights • Long-term dysphagia after CRT for advanced HNC forms a substantial QoL problem. • There is a significant correlation between trismus and laryngeal aspiration. • IMRT results in less swallowing impairment and trismus than conventional RT.
ISSN:	1368-8375 1879-0593
DOI:	10.1016/j.oraloncology.2015.05.003