The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates

The CXC chemokine receptors of fish: Insights into CXCR evolution in the vertebrates

Highlights • CXC chemokine receptors have expanded in teleost fish. • All the known CXCR orthologues found in mammals are present in cartilaginous fish. • The CXCRs appear to have originated from the GPCRs that function in the nervous, sensory, endocrine or reproduction system. • Further characteris...

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Veröffentlicht in:General and comparative endocrinology 2015-05, Vol.215, p.117-131
Hauptverfasser: Zou, Jun, Redmond, Anthony K, Qi, Zhitao, Dooley, Helen, Secombes, Chris J
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biological Evolution
CXC chemokine receptors
Endocrinology & Metabolism
Evolution
Fish
Fishes - genetics
Receptors, CXCR - genetics
Vertebrates
Vertebrates - genetics
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Zusammenfassung:Highlights • CXC chemokine receptors have expanded in teleost fish. • All the known CXCR orthologues found in mammals are present in cartilaginous fish. • The CXCRs appear to have originated from the GPCRs that function in the nervous, sensory, endocrine or reproduction system. • Further characterisation is required to clarify functions of CXCRs in fish.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2015.01.004