Cyclic dipeptides: from bugs to brain

Highlights • CDPs shape the human microbiome. • The human microbiome influences human health. • CDPs are QS signals. • CDPs may be novel agents for human neuroinflammatory diseases.

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Bibliographische Detailangaben
Veröffentlicht in:	Trends in molecular medicine 2014-10, Vol.20 (10), p.551-558
Hauptverfasser:	Bellezza, Ilaria, Peirce, Matthew J, Minelli, Alba
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - metabolism Biological Transport Brain - metabolism Central Nervous System - metabolism diketopiperazines Dipeptides - chemistry Dipeptides - pharmacology Dipeptides - physiology Humans Inflammation - metabolism Inflammation - pathology Microbiota - physiology neurodegeneration Neuroglia - metabolism Neuroglia - pathology neuroinflammation neuroprotection Pathology Peptides, Cyclic - chemistry Peptides, Cyclic - metabolism Peptides, Cyclic - physiology Piperazines - metabolism Quorum Sensing
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Beschreibung
Zusammenfassung:	Highlights • CDPs shape the human microbiome. • The human microbiome influences human health. • CDPs are QS signals. • CDPs may be novel agents for human neuroinflammatory diseases.
ISSN:	1471-4914 1471-499X
DOI:	10.1016/j.molmed.2014.08.003