The dopamine transporter gene may not contribute to susceptibility and the specific personality traits of amphetamine dependence
Highlights • DAT1 gene was analyzed in patients with amphetamine dependence (AD), and different personality. • A weak association was found between the rs27072 polymorphism and development of AD. • The borderline associations were not evident in subsequent correction. • High harm avoidance and novel...
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| Veröffentlicht in: | Drug and alcohol dependence 2015-04, Vol.149, p.100-107 |
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| container_title | Drug and alcohol dependence |
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| creator | Tzeng, Nian-Sheng Lu, Ru-Band Yeh, Hui-Wen Yeh, Yi-Wei Huang, Chang-Chih Yen, Che-Hung Kuo, Shin-Chang Chen, Chun-Yen Chang, Hsin-An Ho, Pei-Shen Cheng, Serena Shih, Mei-Chen Huang, San-Yuan |
| description | Highlights • DAT1 gene was analyzed in patients with amphetamine dependence (AD), and different personality. • A weak association was found between the rs27072 polymorphism and development of AD. • The borderline associations were not evident in subsequent correction. • High harm avoidance and novelty seeking personality may be a risk factor for the development of AD. • DAT1 gene may not contribute to AD susceptibility and specific personality traits. |
| doi_str_mv | 10.1016/j.drugalcdep.2015.01.030 |
| format | Article |
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| ispartof | Drug and alcohol dependence, 2015-04, Vol.149, p.100-107 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Amphetamine dependence Amphetamine-Related Disorders - genetics Amphetamine-Related Disorders - psychology Asian Continental Ancestry Group Case-Control Studies Chinese men DAT1 gene Diagnostic and Statistical Manual of Mental Disorders Dopamine Plasma Membrane Transport Proteins - genetics Exploratory Behavior Genetic Variation Genotype Haplotypes Humans Male Middle Aged Personality - genetics Personality Tests Personality trait Polymorphism, Single Nucleotide Psychiatry |
| title | The dopamine transporter gene may not contribute to susceptibility and the specific personality traits of amphetamine dependence |
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