Magnetic Helical Microswimmers Functionalized with Lipoplexes for Targeted Gene Delivery

Magnetic Helical Microswimmers Functionalized with Lipoplexes for Targeted Gene Delivery

Artificial micro‐/nanoswimmers have various potential applications including minimally invasive diagnosis and targeted therapies, environmental sensing and monitoring, cell manipulation and analysis, and lab‐on‐a‐chip devices. Inspired by natural motile bacteria such as E. Coli, artificial bacterial...

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Veröffentlicht in:Advanced functional materials 2015-03, Vol.25 (11), p.1666-1671
Hauptverfasser: Qiu, Famin, Fujita, Satoshi, Mhanna, Rami, Zhang, Li, Simona, Benjamin R., Nelson, Bradley J.
Format: Artikel
Sprache:eng
Schlagworte:
artificial bacterial flagella
Bacteria
Escherichia coli
Genes
Helical
In vitro testing
Kidneys
lipoplexes
Magnetic fields
magnetic helical microswimmers
plasmid DNA
Rotating
targeted gene delivery
Three dimensional
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Zusammenfassung:Artificial micro‐/nanoswimmers have various potential applications including minimally invasive diagnosis and targeted therapies, environmental sensing and monitoring, cell manipulation and analysis, and lab‐on‐a‐chip devices. Inspired by natural motile bacteria such as E. Coli, artificial bacterial flagella (ABFs) are one kind of magnetic helical microswimmers. ABFs can perform 3D navigation in a controllable fashion with micrometer precision under low‐strength rotating magnetic fields (
ISSN:1616-301X
1616-3028
DOI:10.1002/adfm.201403891