Synthesis of a novel series of fluoroarene derivatives of artemisinin as potent antifungal and anticancer agent
[Display omitted] A series of new fluoroarene derivatives of artemisinin were prepared using Suzuki and Sonogashira cross-coupling reactions. An antifungal and antitumor activity was evaluated against opportunistic pathogen Fusarium oxysporum and Hela cancer cell line. All these derivatives have sho...
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Veröffentlicht in: | Bioorganic & medicinal chemistry letters 2015-08, Vol.25 (16), p.3338-3341 |
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Hauptverfasser: | , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | [Display omitted]
A series of new fluoroarene derivatives of artemisinin were prepared using Suzuki and Sonogashira cross-coupling reactions. An antifungal and antitumor activity was evaluated against opportunistic pathogen Fusarium oxysporum and Hela cancer cell line. All these derivatives have shown moderate to good activity. |
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ISSN: | 0960-894X 1464-3405 |
DOI: | 10.1016/j.bmcl.2015.05.067 |