Can we use serum copeptin levels as a biomarker in obstructive sleep apnea syndrome?

Abstract Objective The aim of this study was to compare serum copeptin levels in patients with obstructive sleep apnea syndrome (OSA) and simple snorers without sleep apnea; and to investigate relationships between copeptin levels and polysomnographic parameters. Methods Serum copeptin levels were d...

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Veröffentlicht in:	Journal of cranio-maxillo-facial surgery 2015-07, Vol.43 (6), p.879-882
Hauptverfasser:	Selcuk, Omer Tarık, Eyigor, Mete, Renda, Levent, Osma, Ustun, Eyigor, Hulya, Selcuk, Nursel Turkoglu, Yılmaz, Mustafa Deniz, Demirkıran, Cansu, Unlu, Hande, Gültekin, Meral
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Apnea Hypopnea Index Biomarkers - blood Body Mass Index Copeptin Dentistry Female Glycopeptides - blood Humans Male Middle Aged Neck - anatomy & histology Oxygen - blood Polysomnography - methods Protein Precursors - blood Serum Sex Factors Simple snorer Sleep apnea Sleep Apnea, Obstructive - blood Sleep Apnea, Obstructive - diagnosis Sleep Stages - physiology Sleep, REM - physiology Snoring - blood Surgery Vasopressin
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Zusammenfassung:	Abstract Objective The aim of this study was to compare serum copeptin levels in patients with obstructive sleep apnea syndrome (OSA) and simple snorers without sleep apnea; and to investigate relationships between copeptin levels and polysomnographic parameters. Methods Serum copeptin levels were determined using enzyme-linked immunosorbent assay in 47 patients with OSA and 12 patients without OSA (control group). Full-night polysomnography was performed in each patient. Patients with OSA were divided into three groups according to their Apnea Hypopnea Index (AHI) scores: mild OSA (5
ISSN:	1010-5182 1878-4119
DOI:	10.1016/j.jcms.2015.03.031