Carbon–Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5‑a]pyrimidines
A new carbon–carbon bond cleavage reaction was developed for the efficient synthesis of multisubstituted pyrazolo[1,5-a]pyrimidines. This base induced reaction of 1,3,5-trisubstituted pentane-1,5-diones and substituted pyrazoles afforded good yields of the pyrazolo[1,5-a]pyrimidines.
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| Veröffentlicht in: | Journal of organic chemistry 2015-07, Vol.80 (13), p.6885-6889 |
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| container_end_page | 6889 |
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| container_issue | 13 |
| container_start_page | 6885 |
| container_title | Journal of organic chemistry |
| container_volume | 80 |
| creator | Saikia, Pallabi Gogoi, Sanjib Boruah, Romesh C |
| description | A new carbon–carbon bond cleavage reaction was developed for the efficient synthesis of multisubstituted pyrazolo[1,5-a]pyrimidines. This base induced reaction of 1,3,5-trisubstituted pentane-1,5-diones and substituted pyrazoles afforded good yields of the pyrazolo[1,5-a]pyrimidines. |
| doi_str_mv | 10.1021/acs.joc.5b00933 |
| format | Article |
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Org. Chem</addtitle><description>A new carbon–carbon bond cleavage reaction was developed for the efficient synthesis of multisubstituted pyrazolo[1,5-a]pyrimidines. This base induced reaction of 1,3,5-trisubstituted pentane-1,5-diones and substituted pyrazoles afforded good yields of the pyrazolo[1,5-a]pyrimidines.</description><subject>Carbon - chemistry</subject><subject>Ketones - chemistry</subject><subject>Molecular Structure</subject><subject>Pyrazoles - chemical synthesis</subject><subject>Pyrazoles - chemistry</subject><subject>Pyrimidines - chemical synthesis</subject><subject>Pyrimidines - chemistry</subject><issn>0022-3263</issn><issn>1520-6904</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kE1Lw0AQhhdRbK2evUmOgqbuRzab9abBL6gofpxEwiS70ZQ0W3cTIZ76F8R_2F9iJNWbc5k5PPMy8yC0S_CYYEqOIHPjqcnGPMVYMraGhoRT7IcSB-toiDGlPqMhG6At56a4K875JhrQEEdMRNEQpTHY1FTLxVc_eKemUl5caniHF-3dacjqwlTH3n1b1a_aFc4zuXfdlHXhmtTVRd3UWnm3rYUPU5oncsiXi094nre2mBWqqLTbRhs5lE7vrPoIPZ6fPcSX_uTm4io-mfjAGKv9nFARUAZYARFC5LmSALlUQSRVFgDDkpOQSZJyJVIFWSCoEIFkEWcyUJyyEdrvc-fWvDXa1cmscJkuS6i0aVxCQskEZYEUHXrUo5k1zlmdJ_PuXLBtQnDyIzbpxCad2GQlttvYW4U36UyrP_7XZAcc9EC_2diq-_XfuG-lqIXU</recordid><startdate>20150702</startdate><enddate>20150702</enddate><creator>Saikia, Pallabi</creator><creator>Gogoi, Sanjib</creator><creator>Boruah, Romesh C</creator><general>American Chemical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20150702</creationdate><title>Carbon–Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5‑a]pyrimidines</title><author>Saikia, Pallabi ; Gogoi, Sanjib ; Boruah, Romesh C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a333t-f127423a0da1777ffd9aaf9d489dc4a309516391b5d7bdac4727749385394d523</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Carbon - chemistry</topic><topic>Ketones - chemistry</topic><topic>Molecular Structure</topic><topic>Pyrazoles - chemical synthesis</topic><topic>Pyrazoles - chemistry</topic><topic>Pyrimidines - chemical synthesis</topic><topic>Pyrimidines - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saikia, Pallabi</creatorcontrib><creatorcontrib>Gogoi, Sanjib</creatorcontrib><creatorcontrib>Boruah, Romesh C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of organic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saikia, Pallabi</au><au>Gogoi, Sanjib</au><au>Boruah, Romesh C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Carbon–Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5‑a]pyrimidines</atitle><jtitle>Journal of organic chemistry</jtitle><addtitle>J. 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| identifier | ISSN: 0022-3263 |
| ispartof | Journal of organic chemistry, 2015-07, Vol.80 (13), p.6885-6889 |
| issn | 0022-3263 1520-6904 |
| language | eng |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Carbon - chemistry Ketones - chemistry Molecular Structure Pyrazoles - chemical synthesis Pyrazoles - chemistry Pyrimidines - chemical synthesis Pyrimidines - chemistry |
| title | Carbon–Carbon Bond Cleavage Reaction: Synthesis of Multisubstituted Pyrazolo[1,5‑a]pyrimidines |
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