1,3,4-Thiadiazole: Synthesis, Reactions, and Applications in Medicinal, Agricultural, and Materials Chemistry

The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2014-05, Vol.114 (10), p.5572-5610
Hauptverfasser:	Hu, Yang, Li, Cui-Yun, Wang, Xiao-Ming, Yang, Yong-Hua, Zhu, Hai-Liang
Format:	Artikel
Sprache:	eng
Schlagworte:	Agricultural chemicals Animals Anti-Infective Agents - chemical synthesis Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology Antiparasitic Agents - chemical synthesis Antiparasitic Agents - chemistry Antiparasitic Agents - toxicity Bacteria - drug effects Biotechnology Chemical engineering Chemical properties Chemical reactions Chemical synthesis Electrochemical Techniques Euglenozoa - drug effects Fungi - drug effects Hydrazides Hydrazines - chemistry Oxadiazoles - chemistry Solid phases Synthesis Thiadiazoles - chemical synthesis Thiadiazoles - chemistry Thiadiazoles - pharmacology
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Beschreibung
Zusammenfassung:	The synthesis, reactions and medicinal applications of the 1,3,4-thiadiazole ring in solution and the solid phase were investigated. The physical and chemical properties of biosostere and the reactions of aromatic and heterocyclic hydrazides with triethyl orthoformate were also explored.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr400131u