Synthesis and Reactivity of 2‑(Carboxymethyl)aziridine Derivatives

Callebaut et al examine the synthesis and reactivity of 2-(carboxymethyl)aziridine derivatives, focusing on topics such as synthesis through N1-C2 bond formation, synthesis via addition reactions to imines, functional group transformations, ring expansion to five-membered rings, and ring opening of...

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Veröffentlicht in:Chemical reviews 2014-08, Vol.114 (16), p.7954-8015
Hauptverfasser: Callebaut, Gert, Meiresonne, Tamara, De Kimpe, Norbert, Mangelinckx, Sven
Format: Artikel
Sprache:eng
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Zusammenfassung:Callebaut et al examine the synthesis and reactivity of 2-(carboxymethyl)aziridine derivatives, focusing on topics such as synthesis through N1-C2 bond formation, synthesis via addition reactions to imines, functional group transformations, ring expansion to five-membered rings, and ring opening of 2-(carboxymethyl)aziridines.
ISSN:0009-2665
1520-6890
DOI:10.1021/cr400582d