Discovery of Bioluminogenic Probes for Aminopeptidase N Imaging

To find an approach that can image the hydrolysis activity of aminopeptidase N (APN) both in vitro and in vivo, three bioluminescent probes have been well designed and synthesized herein. All of them can be recognized and hydrolyzed by APN to produce bioluminescence emission in the presence of firef...

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Veröffentlicht in:	Analytical chemistry (Washington) 2014-03, Vol.86 (5), p.2747-2751
Hauptverfasser:	Li, Jing, Chen, Laizhong, Wu, Wenxiao, Zhang, Wei, Ma, Zhao, Cheng, Yanna, Du, Lupei, Li, Minyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Bioluminescence Biomedical materials CD13 Antigens - metabolism Emission Enzyme kinetics Hydrolysis Imaging In vivo testing In vivo tests Insects Luminescence Molecular Probes Surgical implants Tissues
Online-Zugang:	Volltext
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