Therapeutic Benefits from Nanoparticles: The Potential Significance of Nanoscience in Diseases with Compromise to the Blood Brain Barrier

The use of nanotechnology in medicine is addressed, focusing on the treatment of blood brain barrier (BBB) diseases. Data suggest that nanoparticles hold great promise in improving the early diagnosis and treatment of BBB diseases.

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Bibliographische Detailangaben
Veröffentlicht in:	Chemical reviews 2013-03, Vol.113 (3), p.1877-1903
Hauptverfasser:	Krol, Silke, Macrez, Richard, Docagne, Fabian, Defer, Gilles, Laurent, Sophie, Rahman, Masoud, Hajipour, Mohammad J, Kehoe, Patrick G, Mahmoudi, Morteza
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - drug therapy Alzheimer Disease - physiopathology Barriers Blood Blood-brain barrier Blood-Brain Barrier - drug effects Bradykinin - metabolism Brain Brain - drug effects Brain - metabolism Dementia, Vascular - drug therapy Dementia, Vascular - physiopathology Diseases Drug Delivery Systems Epilepsy - drug therapy Epilepsy - physiopathology Humans Medical services Medical technology Meningitis - physiopathology Multiple sclerosis Multiple Sclerosis - drug therapy Multiple Sclerosis - physiopathology Nanoparticles Nanoparticles - therapeutic use Nanoparticles - toxicity Nanostructure Nanotechnology Reactive Oxygen Species - metabolism Stroke Stroke - drug therapy Stroke - physiopathology
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Beschreibung
Zusammenfassung:	The use of nanotechnology in medicine is addressed, focusing on the treatment of blood brain barrier (BBB) diseases. Data suggest that nanoparticles hold great promise in improving the early diagnosis and treatment of BBB diseases.
ISSN:	0009-2665 1520-6890
DOI:	10.1021/cr200472g