Across all solid organs, adolescent age recipients have worse transplant organ survival than younger age children: A US national registry analysis

Univariate analyses suggest that adolescents have worse long‐term allograft survival versus younger children across different SOT. This study's objective was to determine whether multivariate analyses of a large national database recording all deceased SOT (KI; LI; HR; LU) also show worse adole...

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Veröffentlicht in:Pediatric transplantation 2015-08, Vol.19 (5), p.471-476
Hauptverfasser: Dharnidharka, Vikas R., Lamb, Kenneth E., Zheng, Jie, Schechtman, Kenneth B., Meier-Kriesche, Herwig-Ulf
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Sprache:eng
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Zusammenfassung:Univariate analyses suggest that adolescents have worse long‐term allograft survival versus younger children across different SOT. This study's objective was to determine whether multivariate analyses of a large national database recording all deceased SOT (KI; LI; HR; LU) also show worse adolescent allograft survival in the different organs. Using data from the national Scientific Registry for Transplant Recipients in the USA for pediatric primary SOT from 1989 to 2010, we calculated median half‐lives and constructed K–M graft survival curves. Recipient age at transplant (
ISSN:1397-3142
1399-3046
DOI:10.1111/petr.12464