Physiology and relevance of human adaptive thermogenesis response

Highlights • Brown fat activity defends core temperature while minimizing energy expenditure. • Human brown adipose tissue mass and activity can be expanded. • Human brown adipose tissue activation has beneficial metabolic consequences. • Human brown fat activation alone is insufficient to promote s...

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Veröffentlicht in:	Trends in endocrinology and metabolism 2015-05, Vol.26 (5), p.238-247
Hauptverfasser:	Celi, Francesco S, Le, Trang N, Ni, Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptation, Physiological adaptive thermogenesis Adipose Tissue, Brown - metabolism Adipose Tissue, Brown - physiology Adult Animals brown adipose tissue Capsaicin Carbohydrate Metabolism Cold Temperature Endocrinology & Metabolism Energy Metabolism Humans Models, Animal Obesity Thermogenesis - physiology Weight Loss
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Zusammenfassung:	Highlights • Brown fat activity defends core temperature while minimizing energy expenditure. • Human brown adipose tissue mass and activity can be expanded. • Human brown adipose tissue activation has beneficial metabolic consequences. • Human brown fat activation alone is insufficient to promote significant weight loss.
ISSN:	1043-2760 1879-3061
DOI:	10.1016/j.tem.2015.03.003