Neutrophil-Lymphocyte Ratio (NLR) Could Be Better Predictor than C-reactive Protein (CRP) for Liver Fibrosis in Non-alcoholic Steatohepatitis(NASH)

Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease worldwide. The aims of this study were to assess Neutrophil-Lymphocyte Ratio (NLR) and C-reactive protein (CRP), and their association with liver histology in patients with non-alcoholic steatohepatitis (NASH), chron...

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Veröffentlicht in:	Annals of clinical and laboratory science 2015, Vol.45 (3), p.278-286
Hauptverfasser:	Yilmaz, Hakki, Yalcin, Kadir Serkan, Namuslu, Mehmet, Celik, Huseyin Tugrul, Sozen, Meral, Inan, Osman, Nadir, Isılay, Turkay, Cansel, Akcay, Ali, Kosar, Ali
Format:	Artikel
Sprache:	eng
Schlagworte:	C-Reactive Protein - metabolism Case-Control Studies Cell Count Female Hepatitis B - blood Hepatitis C - blood Humans Liver Cirrhosis - blood Lymphocytes - metabolism Male Middle Aged Multivariate Analysis Neutrophils - metabolism Non-alcoholic Fatty Liver Disease - blood Regression Analysis
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Zusammenfassung:	Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver disease worldwide. The aims of this study were to assess Neutrophil-Lymphocyte Ratio (NLR) and C-reactive protein (CRP), and their association with liver histology in patients with non-alcoholic steatohepatitis (NASH), chronic hepatitis B (HBV), and hepatitis C (HCV). We studied 38 consecutive patients with biopsy-proven NASH, 19 patients with HCV, 45 patients with HBV, and 35 healthy controls who were similar for age and gender. The stage of fibrosis was measured using a 6-point scale. NLR was significantly higher in NASH patients compared to controls, HBV, and HCV patients (p
ISSN:	1550-8080