Palladium-catalyzed ortho-C-H alkenylation of 2-benzyl-1,2,3-triazoles

Palladium-catalyzed ortho-C-H alkenylation of 2-benzyl-1,2,3-triazoles

A mild and efficient method for the direct alkenylation of 2-benzyl-1,2,3-triazoles via Pd-catalyzed C-H bond activation was developed. This protocol was compatible with various substrates and gave the corresponding products in good to excellent yields. Thus, the present study provides a novel and v...

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Veröffentlicht in:Organic & biomolecular chemistry 2015-07, Vol.13 (26), p.7146-7148
Hauptverfasser: He, Ping, Tian, Qingshan, Kuang, Chunxiang
Format: Artikel
Sprache:eng
Schlagworte:
Alkenes - chemistry
Carbon - chemistry
Catalysis
Hydrogen - chemistry
Palladium - chemistry
Triazoles - chemistry
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Zusammenfassung:A mild and efficient method for the direct alkenylation of 2-benzyl-1,2,3-triazoles via Pd-catalyzed C-H bond activation was developed. This protocol was compatible with various substrates and gave the corresponding products in good to excellent yields. Thus, the present study provides a novel and valuable method for the synthesis of 2-benzyl-1,2,3-triazole derivatives.
ISSN:1477-0520
1477-0539
DOI:10.1039/c5ob00973a