Regularized Machine Learning in the Genetic Prediction of Complex Traits: e1004754

[...]we discuss some key future advances, open questions and challenges in this developing field, when moving toward low-frequency variants and cross-phenotype interactions. Multivariate modeling approaches have already been shown to provide improved insights into genetic mechanisms and the interact...

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Veröffentlicht in:	PLoS genetics 2014-11, Vol.10 (11)
Hauptverfasser:	Okser, Sebastian, Pahikkala, Tapio, Airola, Antti, Salakoski, Tapio, Ripatti, Samuli, Aittokallio, Tero
Format:	Artikel
Sprache:	eng
Schlagworte:	Cardiovascular disease Datasets Genomes Genotype & phenotype Health risk assessment
Online-Zugang:	Volltext
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