Valganciclovir for Congenital Cytomegalovirus

To the Editor: In the treatment of congenital cytomegalovirus infection, administration of valganciclovir therapy for 6 months is four times as long as administration for 6 weeks. In this regard, Kimberlin et al. (March 5 issue) 1 do not underscore an important finding of their study; in fact, a comparison of the trends of the viral load in whole blood in the two study groups shows that a significant difference (in favor of the patients who received valganciclovir for 6 months) was evident only from day 56 until day 84, whereas no difference was detectable from 4 to 6 months of . . .