Synthesis of N-vinylindoles through copper catalyzed cyclization reaction of N-(2-alkynylphenyl)imine

Synthesis of N-vinylindoles through copper catalyzed cyclization reaction of N-(2-alkynylphenyl)imine

A copper(II)-catalyzed cyclization reaction of N-(2-alkynylphenyl)imine was developed. This strategy provided an effective procedure for the synthesis of substituted N-vinylindoles in moderate to good yields.

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Veröffentlicht in:Organic & biomolecular chemistry 2015-07, Vol.13 (25), p.6931-6934
Hauptverfasser: Wang, Zhi-Qiang, Zhang, Xu, Yu, Lin-Tao, Mao, Wu-Tao, Chen, Chang-Zhong, Xu, Kun
Format: Artikel
Sprache:eng
Schlagworte:
Alkenes - chemical synthesis
Alkenes - chemistry
Alkynes - chemical synthesis
Alkynes - chemistry
Catalysis
Copper - chemistry
Cyclization
Imines - chemical synthesis
Imines - chemistry
Indoles - chemical synthesis
Indoles - chemistry
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Beschreibung
Zusammenfassung:A copper(II)-catalyzed cyclization reaction of N-(2-alkynylphenyl)imine was developed. This strategy provided an effective procedure for the synthesis of substituted N-vinylindoles in moderate to good yields.
ISSN:1477-0520
1477-0539
DOI:10.1039/c5ob00746a