Carbohydrate intake and insulin requirement in children, adolescents and young adults with cystic fibrosis-related diabetes: A multicenter comparison to type 1 diabetes

Summary Background & aims In cystic fibrosis-related diabetes (CFRD), energy needs differ from type 1 (T1D) or type 2 diabetes, and endogenous insulin secretion is not totally absent. We analyzed whether daily carbohydrate intake, its diurnal distribution and insulin requirement per 11 g of carb...

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Veröffentlicht in:	Clinical nutrition (Edinburgh, Scotland) Scotland), 2015-08, Vol.34 (4), p.732-738
Hauptverfasser:	Scheuing, Nicole, Thon, Angelika, Konrad, Katja, Bauer, Maria, Karsten, Claudia, Meissner, Thomas, Seufert, Jochen, Schönau, Eckhard, Schöfl, Christof, Woelfle, Joachim, Holl, Reinhard W
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Blood Glucose Body Mass Index Child Cystic fibrosis Cystic Fibrosis - drug therapy Diabetes mellitus Diabetes Mellitus, Type 1 - drug therapy Dietary carbohydrates Dietary Carbohydrates - administration & dosage Dietary Carbohydrates - blood Dose-Response Relationship, Drug Energy Intake Female Gastroenterology and Hepatology Humans Insulin - administration & dosage Insulin - blood Insulin dose Linear Models Male Multivariate Analysis Nutritional Requirements Prospective Studies Recommended Dietary Allowances Young Adult
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Zusammenfassung:	Summary Background & aims In cystic fibrosis-related diabetes (CFRD), energy needs differ from type 1 (T1D) or type 2 diabetes, and endogenous insulin secretion is not totally absent. We analyzed whether daily carbohydrate intake, its diurnal distribution and insulin requirement per 11 g of carbohydrate differ between CFRD and T1D. Methods Anonymized data of 223 CFRD and 36,780 T1D patients aged from 10 to
ISSN:	0261-5614 1532-1983
DOI:	10.1016/j.clnu.2014.08.016