Multifunctional inverse opal particles for drug delivery and monitoring

Particle-based delivery systems have a demonstrated value for drug discovery and development. Here, we report a new type of particle-based delivery system that has controllable release and is self-monitoring. The particles were composed of poly(N-isopropylacrylamide) (pNIPAM) hydrogel with an invers...

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Veröffentlicht in:Nanoscale 2015-06, Vol.7 (24), p.10590-10594
Hauptverfasser: Zhang, Bin, Cheng, Yao, Wang, Huan, Ye, Baofen, Shang, Luoran, Zhao, Yuanjin, Gu, Zhongze
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Sprache:eng
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Zusammenfassung:Particle-based delivery systems have a demonstrated value for drug discovery and development. Here, we report a new type of particle-based delivery system that has controllable release and is self-monitoring. The particles were composed of poly(N-isopropylacrylamide) (pNIPAM) hydrogel with an inverse opal structure. The presence of macropores in the particles provides channels for active drug loading and release from the materials.
ISSN:2040-3364
2040-3372
DOI:10.1039/c5nr02324f