Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment
Background The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism. Results It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship s...
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| Veröffentlicht in: | European journal of clinical pharmacology 2015-07, Vol.71 (7), p.773-799 |
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| container_end_page | 799 |
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| container_issue | 7 |
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| container_title | European journal of clinical pharmacology |
| container_volume | 71 |
| creator | Quetglas, E. G. Armuzzi, A. Wigge, S. Fiorino, G. Barnscheid, L. Froelich, M. Danese, Silvio |
| description | Background
The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
Results
It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics. |
| doi_str_mv | 10.1007/s00228-015-1862-7 |
| format | Article |
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The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
Results
It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.</description><identifier>ISSN: 0031-6970</identifier><identifier>EISSN: 1432-1041</identifier><identifier>DOI: 10.1007/s00228-015-1862-7</identifier><identifier>PMID: 26008212</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Animals ; Anti-Inflammatory Agents - adverse effects ; Anti-Inflammatory Agents - pharmacokinetics ; Anti-Inflammatory Agents - therapeutic use ; Biomedical and Life Sciences ; Biomedicine ; Colitis, Ulcerative - diagnosis ; Colitis, Ulcerative - drug therapy ; Colitis, Ulcerative - immunology ; Crohn Disease - diagnosis ; Crohn Disease - drug therapy ; Crohn Disease - immunology ; Crohn's disease ; Drug Monitoring ; Gastrointestinal Agents - adverse effects ; Gastrointestinal Agents - pharmacokinetics ; Gastrointestinal Agents - therapeutic use ; Humans ; Inflammatory bowel disease ; Kinetics ; Pharmacogenetics ; Pharmacology ; Pharmacology/Toxicology ; Remission Induction ; Review Article ; Treatment Outcome</subject><ispartof>European journal of clinical pharmacology, 2015-07, Vol.71 (7), p.773-799</ispartof><rights>Springer-Verlag Berlin Heidelberg 2015</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c430t-ff2f1c6a222498345ba2108179bd61b2af04960203bcae98ca0afeae02ea136c3</citedby><cites>FETCH-LOGICAL-c430t-ff2f1c6a222498345ba2108179bd61b2af04960203bcae98ca0afeae02ea136c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00228-015-1862-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00228-015-1862-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26008212$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Quetglas, E. G.</creatorcontrib><creatorcontrib>Armuzzi, A.</creatorcontrib><creatorcontrib>Wigge, S.</creatorcontrib><creatorcontrib>Fiorino, G.</creatorcontrib><creatorcontrib>Barnscheid, L.</creatorcontrib><creatorcontrib>Froelich, M.</creatorcontrib><creatorcontrib>Danese, Silvio</creatorcontrib><title>Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment</title><title>European journal of clinical pharmacology</title><addtitle>Eur J Clin Pharmacol</addtitle><addtitle>Eur J Clin Pharmacol</addtitle><description>Background
The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
Results
It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.</description><subject>Animals</subject><subject>Anti-Inflammatory Agents - adverse effects</subject><subject>Anti-Inflammatory Agents - pharmacokinetics</subject><subject>Anti-Inflammatory Agents - therapeutic use</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Colitis, Ulcerative - diagnosis</subject><subject>Colitis, Ulcerative - drug therapy</subject><subject>Colitis, Ulcerative - immunology</subject><subject>Crohn Disease - diagnosis</subject><subject>Crohn Disease - drug therapy</subject><subject>Crohn Disease - immunology</subject><subject>Crohn's disease</subject><subject>Drug Monitoring</subject><subject>Gastrointestinal Agents - adverse effects</subject><subject>Gastrointestinal Agents - pharmacokinetics</subject><subject>Gastrointestinal Agents - therapeutic use</subject><subject>Humans</subject><subject>Inflammatory bowel disease</subject><subject>Kinetics</subject><subject>Pharmacogenetics</subject><subject>Pharmacology</subject><subject>Pharmacology/Toxicology</subject><subject>Remission Induction</subject><subject>Review Article</subject><subject>Treatment Outcome</subject><issn>0031-6970</issn><issn>1432-1041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kUFr3DAQhUVpaTZpf0AvQdBLLm5nJK8t9xZC2hQChZKexVgeJU5sayPZCfvvq2WTUAKFgYGnb96IeUJ8QviCAPXXBKCUKQDXBZpKFfUbscJSqwKhxLdiBaCxqJoaDsRhSreQwQb0e3GgKgCjUK1E-M0PPT9KinPvBv4mr25Ybm4ojuTCXT9xlpOkqXsRu-1E404MXnZxuU5ySdzJfsrlBxpHmkPcyjY88iC7PjEllnNkmkee5g_inach8cenfiT-fD-_OrsoLn_9-Hl2elm4UsNceK88uoqUUmVjdLluSSEYrJu2q7BV5KFsKlCgW0fcGEdAnolBMaGunD4SJ3vfTQz3C6fZjn1yPAw0cViSxcoYgHWDkNHPr9DbsMQp_25H1WVT19pkCveUiyGlyN5uYj9S3FoEu0vD7tOw-ch2l4at88zxk_PSjty9TDyfPwNqD6T8NF1z_Gf1f13_Ah-Qle4</recordid><startdate>20150701</startdate><enddate>20150701</enddate><creator>Quetglas, E. 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G.</creatorcontrib><creatorcontrib>Armuzzi, A.</creatorcontrib><creatorcontrib>Wigge, S.</creatorcontrib><creatorcontrib>Fiorino, G.</creatorcontrib><creatorcontrib>Barnscheid, L.</creatorcontrib><creatorcontrib>Froelich, M.</creatorcontrib><creatorcontrib>Danese, Silvio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of clinical pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Quetglas, E. G.</au><au>Armuzzi, A.</au><au>Wigge, S.</au><au>Fiorino, G.</au><au>Barnscheid, L.</au><au>Froelich, M.</au><au>Danese, Silvio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment</atitle><jtitle>European journal of clinical pharmacology</jtitle><stitle>Eur J Clin Pharmacol</stitle><addtitle>Eur J Clin Pharmacol</addtitle><date>2015-07-01</date><risdate>2015</risdate><volume>71</volume><issue>7</issue><spage>773</spage><epage>799</epage><pages>773-799</pages><issn>0031-6970</issn><eissn>1432-1041</eissn><abstract>Background
The following review is a compilation of the recent advances and knowledge on the behaviour of the most frequently used compounds to treat inflammatory bowel disease in an organism.
Results
It considers clinical aspects of each entity and the pharmacokinetic/pharmacodynamic relationship supported by the use of plasma monitoring, tissue concentrations, and certain aspects derived from pharmacogenetics.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>26008212</pmid><doi>10.1007/s00228-015-1862-7</doi><tpages>27</tpages></addata></record> |
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| subjects | Animals Anti-Inflammatory Agents - adverse effects Anti-Inflammatory Agents - pharmacokinetics Anti-Inflammatory Agents - therapeutic use Biomedical and Life Sciences Biomedicine Colitis, Ulcerative - diagnosis Colitis, Ulcerative - drug therapy Colitis, Ulcerative - immunology Crohn Disease - diagnosis Crohn Disease - drug therapy Crohn Disease - immunology Crohn's disease Drug Monitoring Gastrointestinal Agents - adverse effects Gastrointestinal Agents - pharmacokinetics Gastrointestinal Agents - therapeutic use Humans Inflammatory bowel disease Kinetics Pharmacogenetics Pharmacology Pharmacology/Toxicology Remission Induction Review Article Treatment Outcome |
| title | Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment |
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