Partial protection and abomasal cytokine expression in sheep experimentally infected with Haemonchus contortus and pre-treated with Taenia hydatigena vesicular concentrate

•The administration of a Taenia hydatigena larvae vesicular concentrate (ThLVC) reduced the implantation of H. contortus larvae in lambs.•ThLVC-induced protection is associated to the expression of certain types of cytokines.•The ThLVC is a non-specific immune stimulator for the abomasal immune resp...

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Veröffentlicht in:Veterinary parasitology 2015-06, Vol.211 (1-2), p.60-66
Hauptverfasser: Buendía-Jiménez, J.A., Muñoz-Guzmán, M.A., Vega-López, M.A., Cuenca-Verde, C., Martínez-Labat, J.P., Cuéllar-Ordaz, J.A., Alba-Hurtado, F.
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Sprache:eng
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Zusammenfassung:•The administration of a Taenia hydatigena larvae vesicular concentrate (ThLVC) reduced the implantation of H. contortus larvae in lambs.•ThLVC-induced protection is associated to the expression of certain types of cytokines.•The ThLVC is a non-specific immune stimulator for the abomasal immune response. The abomasal expression of IL-2, IL-4, IL-6, IL-10 and IFNγ in lambs experimentally infected with Haemonchus contortus and its relationship to protection induced by a Taenia hydatigena larvae vesicular concentrate (ThLVC) were evaluated. The lambs that were only infected with H. contortus larvae showed a worm burden greater (p
ISSN:0304-4017
1873-2550
DOI:10.1016/j.vetpar.2015.04.019