Muscular arterial impedance in dogs with chronic degenerative mitral valve disease

Systemic vascular impedance represents the retrograde strength of the blood flow to the left ventricle, thus it is one of the main compounds of afterload. Mitral regurgitation is markedly sensitive to afterload alterations. The purpose of this study was to evaluate muscular arterial impedance in dogs with chronic degenerative mitral valve disease (CDMVD) by use of duplex Doppler ultrasonography (DDU), since its technique there was not used before to determine impedance index in dogs with CDMVD. For this purpose, ten healthy dogs and ten dogs with CDMVD were used. Some parameters related to blood flow impedance in the common femoral artery were measured by DDU: pulsatility index (PI), resistance index (RI), high-resistance index (HRI), and acceleration velocity (AC) and deceleration velocity (DC) of the systolic peak. The results showed that RI and HRI were significantly higher in animals with CDMVD than in healthy animals. These findings showed that DDU provides quantitative data related to vascular impedance. Broader studies may therefore provide new aspects related to physiopathology and therapy in CDMVD patients.