Mesoporous MCM-41-nPr-NHSO sub(3)H as novel and effective nanoreactor catalyst for the synthesis of multi-substituted imidazoles under solvent-free conditions

Herein, we report the synthesis and application of mesoporous siliceous MCM-41-nPr-NHSO sub(3)H, which was characterized by XRD, IR, TGA and nitrogen physisorption measurements. MCM-41-nPr-NHSO sub(3)H was used as an efficient heterogeneous catalyst for the one-pot synthesis of imidazoles derivatives under solvent free conditions with good to excellent yields. The present methodology offers several advantages such as less waste, simplicity of procedure, short reaction time, easy and quick isolation of the products.