Bactibilia and Antibiotic Resistance in Elective Cholecysctectomy: An Updated Ecologic Survey

Background: The role of bactibilia as a risk factor for an unfavorable outcome during biliary disease or surgical procedures remains obscure. Our aim was to identify possible risk factors for bactibilia and their possible relations to complications after elective cholecystectomy. As secondary aims,...

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Veröffentlicht in:Surgical infections 2015-06, Vol.16 (3), p.287-292
Hauptverfasser: Troyano Escribano, Daniel, Balibrea Del Castillo, José M., Molinos Abós, Sònia, Vicente, Ausina Ruiz, Fernandez-Llamazares Rodriguez, Jaime, Oller Sales, Benjamin
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container_end_page 292
container_issue 3
container_start_page 287
container_title Surgical infections
container_volume 16
creator Troyano Escribano, Daniel
Balibrea Del Castillo, José M.
Molinos Abós, Sònia
Vicente, Ausina Ruiz
Fernandez-Llamazares Rodriguez, Jaime
Oller Sales, Benjamin
description Background: The role of bactibilia as a risk factor for an unfavorable outcome during biliary disease or surgical procedures remains obscure. Our aim was to identify possible risk factors for bactibilia and their possible relations to complications after elective cholecystectomy. As secondary aims, composition and antibiotic resistance patterns were studied. Methods: Bile and gallbladder mucosa samples from 358 elective cholecystectomies were collected prospectively between June 2009 and June 2012. Ordinary microbiologic cultures and antibiograms were performed. All pre-operative factors associated with bactibilia were studied by stepwise logistic regression multivariable analysis. Results: The bacteria isolated most frequently from 103 positive cultures were Escherichia coli (21.3%), Enterococcus spp. (14.7%), and Enterobacter spp. (14.7%) with a global amoxicillin-clavulanic acid resistance rate of 53.7%. Age >65 y, male gender, previous instrumentation or disease of the biliary tract, and high American Society of Anesthesiologists score were independent risk factors. No correlation was found between bactibilia and surgical complications. Conclusions: Although the influence of bactibilia in developing surgical complications is limited, its composition and the high rate of resistance can be influential enough to modify antibiotic treatment in biliary tract infections, especially in high-risk patients.
doi_str_mv 10.1089/sur.2014.023
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Our aim was to identify possible risk factors for bactibilia and their possible relations to complications after elective cholecystectomy. As secondary aims, composition and antibiotic resistance patterns were studied. Methods: Bile and gallbladder mucosa samples from 358 elective cholecystectomies were collected prospectively between June 2009 and June 2012. Ordinary microbiologic cultures and antibiograms were performed. All pre-operative factors associated with bactibilia were studied by stepwise logistic regression multivariable analysis. Results: The bacteria isolated most frequently from 103 positive cultures were Escherichia coli (21.3%), Enterococcus spp. (14.7%), and Enterobacter spp. (14.7%) with a global amoxicillin-clavulanic acid resistance rate of 53.7%. Age &gt;65 y, male gender, previous instrumentation or disease of the biliary tract, and high American Society of Anesthesiologists score were independent risk factors. No correlation was found between bactibilia and surgical complications. 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Our aim was to identify possible risk factors for bactibilia and their possible relations to complications after elective cholecystectomy. As secondary aims, composition and antibiotic resistance patterns were studied. Methods: Bile and gallbladder mucosa samples from 358 elective cholecystectomies were collected prospectively between June 2009 and June 2012. Ordinary microbiologic cultures and antibiograms were performed. All pre-operative factors associated with bactibilia were studied by stepwise logistic regression multivariable analysis. Results: The bacteria isolated most frequently from 103 positive cultures were Escherichia coli (21.3%), Enterococcus spp. (14.7%), and Enterobacter spp. (14.7%) with a global amoxicillin-clavulanic acid resistance rate of 53.7%. Age &gt;65 y, male gender, previous instrumentation or disease of the biliary tract, and high American Society of Anesthesiologists score were independent risk factors. No correlation was found between bactibilia and surgical complications. 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subjects Adolescent
Adult
Aged
Aged, 80 and over
Bacteria - classification
Bacteria - drug effects
Bacteria - isolation & purification
Bacteriological Techniques
Bile - microbiology
Cholecystectomy
Drug Resistance, Bacterial
Female
Gallbladder - microbiology
Humans
Male
Middle Aged
Original Articles
Prospective Studies
Young Adult
title Bactibilia and Antibiotic Resistance in Elective Cholecysctectomy: An Updated Ecologic Survey
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