Treatment of cardiac disease by inhalation of atmospheric pressure plasma

The use of inhaled plasma, generated by an atmospheric-pressure plasma (APP) reactor, in a rat myocardial infarction (MI) model resulted in an increased saturation pulse oxygen (SpO2) level in the blood, which suggests that this method can be beneficial in restoring heart function following cardiac ischemia. Additionally, in vivo blood pressure decreased from 89/81 to 73/60 mmHg in the abdominal aorta during plasma inhalation. The nitric oxide (NO) concentration in the abdominal aorta increased after 20 s of plasma inhalation, reaching a maximum value at about 160 s and gradually decreased thereafter.