Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs-fimbriae and α-hemolysin form the pathogenicity island II of the uropathogenic Escherichia coli strain J96

The uropathogenic Escherichia coli strain J96 (04:K6) is able to produce four adherence factors [P-fimbriae ( pap and prs), F1C-fimbriae ( foc) and Type 1-fimbriae ( fim)], two α-hemolysins ( hfyI and II) and the cytotoxic necrotizing factor type 1 ( cnf1). Using phenotypic test systems and genotypi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	FEMS microbiology letters 1995-02, Vol.126 (2), p.189-195
Hauptverfasser:	Blum, Gabriele, Falbo, Vincenzo, Caprioli, Alfredo, Hacker, Jörg
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesins, Bacterial - genetics Bacterial Toxins - genetics Bacteriology Biological and medical sciences Chromosome Mapping Cytotoxic necrotizing factor 1 Cytotoxins - genetics Escherichia coli Escherichia coli - genetics Escherichia coli Proteins Fundamental and applied biological sciences. Psychology Genetics Hemolysin Hemolysin Proteins - genetics Microbiology Multigene Family Mutation P-fimbriae Pathogenicity islands Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Urovirulence
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The uropathogenic Escherichia coli strain J96 (04:K6) is able to produce four adherence factors [P-fimbriae ( pap and prs), F1C-fimbriae ( foc) and Type 1-fimbriae ( fim)], two α-hemolysins ( hfyI and II) and the cytotoxic necrotizing factor type 1 ( cnf1). Using phenotypic test systems and genotypic analysis, it has been shown that the mutant strain J96-M1 has lost the hlyII, prs and cnf1 genes. The three virulence associated determinants are linked on one particular region on the chromosome, which is termed ‘pathogenicity island II’ (Pai II).
ISSN:	0378-1097 1574-6968
DOI:	10.1016/0378-1097(95)00009-T