Delayed Gastric Emptying After Pancreaticoduodenectomy. Risk Factors, Predictors of Severity and Outcome. A Single Center Experience of 588 Cases

Background Delayed gastric emptying (DGE) is a common complication after pancreaticoduodenectomy (PD). This study was designed to evaluate perioperative risk variables for DGE after PD and analyze the factors that predict its severity. Patients and Method Demographic data, preoperative, intraoperati...

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Veröffentlicht in:Journal of gastrointestinal surgery 2015-06, Vol.19 (6), p.1093-1100
Hauptverfasser: El Nakeeb, Ayman, Askr, Waleed, Mahdy, Youssef, Elgawalby, Ahmed, El sorogy, Mohamed, Abu Zeied, Mostaffa, Abdallah, Talaat, Abd elwahab, Mohamed
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Sprache:eng
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Zusammenfassung:Background Delayed gastric emptying (DGE) is a common complication after pancreaticoduodenectomy (PD). This study was designed to evaluate perioperative risk variables for DGE after PD and analyze the factors that predict its severity. Patients and Method Demographic data, preoperative, intraoperative, and postoperative variables were collected. Results A total of 588 consecutive patients underwent PD. One hundred and five patients (17.9 %) developed DGE of any type. Forty-three patients (7.3 %) had a type A, 53 patients (9.01 %) had DGE type B, and the remaining nine patients (1.5 %) had DGE type C. BMI > 25, diabetes mellitus (DM), preoperative biliary drainage, retrocolic reconstruction, type of pancreatic reconstruction, presence of complications, postoperative pancreatic fistula (POPF), and bile leaks were significantly associated with a higher incidence of DGE. Thirty-three (31.4 %) patients were diagnosed as primary DGE, while 72 (68.5 %) patients had DGE secondary to concomitant complications. Type B and C DGE were significantly noticed in secondary DGE ( P  = 0.04). Hospital stay was significantly shorter in primary DGE. Conclusion Retrocolic GJ, DM, presence of complications, type of pancreatic reconstruction, and severity of POPF were independent significant risk factors for development of DGE. Type B and C DGE were significantly more in secondary DGE.
ISSN:1091-255X
1873-4626
DOI:10.1007/s11605-015-2795-2