Continuous production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) by Alcaligenes eutrophus

Copolymers of 3-hydroxybutyrate (3HB) and 3-hydroxyvalerate (3HV) were produced in a continuous culture of Alcaligenes eutrophus with 17.5 gl super(-1) of fructose and 2.5 gl super(-1) of pentanoic acid in the feed. The P(3HB-co-3HV) productivity was maximal at a dilution rate of 0.17h super(-1) and...

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Veröffentlicht in:Biotechnology letters 1995-03, Vol.17 (3), p.281-284
Hauptverfasser: KOYAMA, N, DOI, Y
Format: Artikel
Sprache:eng
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Zusammenfassung:Copolymers of 3-hydroxybutyrate (3HB) and 3-hydroxyvalerate (3HV) were produced in a continuous culture of Alcaligenes eutrophus with 17.5 gl super(-1) of fructose and 2.5 gl super(-1) of pentanoic acid in the feed. The P(3HB-co-3HV) productivity was maximal at a dilution rate of 0.17h super(-1) and yielded 0.31 gl super(-1)h super(-1) under an ammonium-limited condition. The 3HV content in copolymers increased from 11 to 79 mol% as the dilution rate of cells was increased from 0.06 to 0.32h super(-1).
ISSN:0141-5492
1573-6776
DOI:10.1007/BF01190637