Reverse genetics tools in zebrafish: A forward dive into endocrinology

Reverse genetics tools in zebrafish: A forward dive into endocrinology

Highlights ► Zebrafish is a genetic model system ideally suitable for comparative endocrinology. ► Both heritable and transient reverse genetic tools are available in zebrafish. ► Transgenics using the Tol2 system enable sophisticated transgenic manipulations.

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Bibliographische Detailangaben
Veröffentlicht in:General and comparative endocrinology 2013-07, Vol.188, p.303-308
Hauptverfasser: Sugano, Yuya, Neuhauss, Stephan C.F
Format: Artikel
Sprache:eng
Schlagworte:
animal models
Animals
Animals, Genetically Modified
Danio rerio
endocrinology
Endocrinology & Metabolism
Endocrinology - methods
genetically modified organisms
human diseases
Models, Animal
Reverse genetics
Reverse Genetics - methods
Transgenesis
Zebrafish
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Beschreibung
Zusammenfassung:Highlights ► Zebrafish is a genetic model system ideally suitable for comparative endocrinology. ► Both heritable and transient reverse genetic tools are available in zebrafish. ► Transgenics using the Tol2 system enable sophisticated transgenic manipulations.
ISSN:0016-6480
1095-6840
DOI:10.1016/j.ygcen.2013.02.002