Donor–recipient matching in lung transplantation: which variables are important?

OBJECTIVES Donor to recipient (D/R) matching in lung transplantation (LTx) is usually directed by blood group (identity or compatibility) and predicted total lung capacity (pTLC) based on height and age. Other donor (D) and recipient (R) characteristics such as cytomegalovirus (CMV) serology (±), ge...

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Veröffentlicht in:European journal of cardio-thoracic surgery 2015-06, Vol.47 (6), p.974-983
Hauptverfasser: Demir, Adalet, Coosemans, Willy, Decaluwé, Herbert, De Leyn, Paul, Nafteux, Philippe, Van Veer, Hans, Verleden, Geert M., Van Raemdonck, Dirk
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Sprache:eng
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Zusammenfassung:OBJECTIVES Donor to recipient (D/R) matching in lung transplantation (LTx) is usually directed by blood group (identity or compatibility) and predicted total lung capacity (pTLC) based on height and age. Other donor (D) and recipient (R) characteristics such as cytomegalovirus (CMV) serology (±), gender [male (M)/ female (F)] and age are often ignored, but the impact of D/R mismatch for these variables and their combinations on outcome is less investigated. METHODS The early and late outcomes in 461 lung recipients (149 single-lung and 312 double-lung) transplanted between July 1991 and December 2009 were explored, comparing different D/R combinations for gender (M/F), age (
ISSN:1010-7940
1873-734X
DOI:10.1093/ejcts/ezu340