Hilar and Mediastinal Lymphadenopathy with Hypersensitivity Pneumonitis Induced by Penicillin

A 54-year-old Japanese man demonstrated a sultamicillin-induced hilar and mediastinal lymphadenopathy with hypersensitivity pneumonitis. A positive lymphocyte stimulation test for sultamicillin and a decreased CD4/CD8 ratio of lymphocytes in BAL fluid suggested that an alteration in cell-mediated me...

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Veröffentlicht in:	Chest 1992-12, Vol.102 (6), p.1907-1909
Hauptverfasser:	Yonemaru, Makoto, Mizuguchi, Yasuhiro, Kasuga, Ikuma, Utsumi, Kenta, Ichinose, Yuichi, Toyama, Keisuke
Format:	Artikel
Sprache:	eng
Schlagworte:	Alveolitis, Extrinsic Allergic - chemically induced Ampicillin - adverse effects Axilla Case studies Causes of Clavicle Complications and side effects Drug allergy Drug Eruptions - etiology Drug Therapy, Combination - adverse effects Groin Humans Hypersensitivity pneumonitis Lung Lymphadenopathy Lymphatic Diseases - chemically induced Male Mediastinum Middle Aged Penicillin Sulbactam - adverse effects
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Zusammenfassung:	A 54-year-old Japanese man demonstrated a sultamicillin-induced hilar and mediastinal lymphadenopathy with hypersensitivity pneumonitis. A positive lymphocyte stimulation test for sultamicillin and a decreased CD4/CD8 ratio of lymphocytes in BAL fluid suggested that an alteration in cell-mediated mechanisms was responsible for the patient's symptoms.
ISSN:	0012-3692 1931-3543
DOI:	10.1378/chest.102.6.1907