Microbial individuality: how single-cell heterogeneity enables population level strategies

Microbial individuality: how single-cell heterogeneity enables population level strategies

Highlights • Gene expression can be surprisingly dynamic and noisy. • Cell to cell heterogeneity in gene expression state is a widespread phenomenon. • Phenotypic diversity can be generated by both stochastic and deterministic mechanisms. • Phenotypic diversity can implement population level functio...

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Veröffentlicht in:Current opinion in microbiology 2015-04, Vol.24, p.104-112
Hauptverfasser: Martins, Bruno MC, Locke, James CW
Format: Artikel
Sprache:eng
Schlagworte:
Bacteria - metabolism
Gene Expression Regulation, Bacterial
Microbiological Phenomena
Pathology
Phenotype
Single-Cell Analysis
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Zusammenfassung:Highlights • Gene expression can be surprisingly dynamic and noisy. • Cell to cell heterogeneity in gene expression state is a widespread phenomenon. • Phenotypic diversity can be generated by both stochastic and deterministic mechanisms. • Phenotypic diversity can implement population level functions.
ISSN:1369-5274
1879-0364
DOI:10.1016/j.mib.2015.01.003