The evaluation of bone metabolism in children with renal transplantation

This study aims to evaluate BMD and bone biomarkers and to investigate the effects of immunosuppressives on bone disease after RTx. Thirty‐three RTR aged 16.7 ± 3.7 yr and healthy controls (n = 32) were enrolled. There was no difference between pre‐RTx BMD and BMD at the time of study (45.9 ± 30.9 m...

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Veröffentlicht in:	Pediatric transplantation 2015-06, Vol.19 (4), p.351-357
Hauptverfasser:	Büyükkaragöz, Bahar, Bakkaloglu, Sevcan A., Kandur, Yaşar, Isiyel, Emel, Akcaboy, Meltem, Buyan, Necla, Hasanoglu, Enver
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Anthropometry Biomarkers - metabolism Bone and Bones - metabolism Bone and Bones - pathology Bone Density bone metabolism bone mineral density Case-Control Studies Child Child, Preschool children corticosteroids Female Fibroblast Growth Factors - metabolism Humans Immunosuppressive Agents - therapeutic use Kidney Transplantation Male Osteoprotegerin - metabolism Parathyroid Hormone - metabolism RANK Ligand - metabolism Renal Insufficiency - blood Renal Insufficiency - pathology Renal Insufficiency - surgery renal transplantation Vitamin D - analogs & derivatives Vitamin D - metabolism Young Adult
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Beschreibung
Zusammenfassung:	This study aims to evaluate BMD and bone biomarkers and to investigate the effects of immunosuppressives on bone disease after RTx. Thirty‐three RTR aged 16.7 ± 3.7 yr and healthy controls (n = 32) were enrolled. There was no difference between pre‐RTx BMD and BMD at the time of study (45.9 ± 30.9 months after RTx), while both values were lower than controls (p
ISSN:	1397-3142 1399-3046
DOI:	10.1111/petr.12469