A local renin-angiotensin-like system in the heart of an African lungfish ( Protopterus annectens)

The presence of components of a renin-angiotensin system was investigated in the heart of an African lungfish Protopterus annectens. A renin-like activity is present in heart homogenates. The activity reaches its maximum after 90 min of incubation at 20°C. By a spectrophotometric assay, an angiotens...

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Veröffentlicht in:Comparative biochemistry and physiology. A, Comparative physiology Comparative physiology, 1995, Vol.110 (3), p.229-233
Hauptverfasser: Masini, Maria Angela, Devecchi, Monica, Napoli, Laura, Uva, Bianca Maria
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container_title Comparative biochemistry and physiology. A, Comparative physiology
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creator Masini, Maria Angela
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Napoli, Laura
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description The presence of components of a renin-angiotensin system was investigated in the heart of an African lungfish Protopterus annectens. A renin-like activity is present in heart homogenates. The activity reaches its maximum after 90 min of incubation at 20°C. By a spectrophotometric assay, an angiotensin converting enzyme-like activity was detected. By immunohistochemistry Ile 5-Angiotensin II immunoreactive cardiocytes were demonstrated in the atrium and bulbus. Our data indicate that probably a local renin-angiotensin-like system is present in the heart of Protopterus annectens.
doi_str_mv 10.1016/0300-9629(94)00171-O
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ispartof Comparative biochemistry and physiology. A, Comparative physiology, 1995, Vol.110 (3), p.229-233
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language eng
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subjects Angiotensin converting enzyme
Angiotensin II
Dipnoan
Freshwater
Heart
Lungfish
Protopterus annectens
Renin activity
Renin-angiotensin system
title A local renin-angiotensin-like system in the heart of an African lungfish ( Protopterus annectens)
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