Effects of algae extracts from New York/New Jersey coastline, USA on cultured mammalian cells
The toxicity of antimicrobial extracts of the algae Fucus spiralis and Fucus vesiculosus was determined by an in-vitro technique on cultured Chinese Hamster Ovary cells as an alternative to animal testing. The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plat...
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| Veröffentlicht in: | Bulletin of environmental contamination and toxicology 1993-09, Vol.51 (3), p.367-373 |
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| container_issue | 3 |
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| container_title | Bulletin of environmental contamination and toxicology |
| container_volume | 51 |
| creator | Dilorenzo, A.M Lustigman, B Correa, M Aglione, A |
| description | The toxicity of antimicrobial extracts of the algae Fucus spiralis and Fucus vesiculosus was determined by an in-vitro technique on cultured Chinese Hamster Ovary cells as an alternative to animal testing. The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plating efficiency of the cells were used as markers. F. spirilis showed less toxicity as determined by greater plating efficiency and ability to move by mitosis into areas free of attached cells than F. vesiculosis. |
| doi_str_mv | 10.1007/BF00201754 |
| format | Article |
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The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plating efficiency of the cells were used as markers. 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Lustigman, B ; Correa, M ; Aglione, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c382t-7a1f1eebcf9ef2835e8d3d7fe72fbb660dc49fce4492095668bfe277653894513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1993</creationdate><topic>ALTERNATIVAS A ENSAYOS CON ANIMALES</topic><topic>ALTERNATIVE ANIMAL DE LABORATOIRE</topic><topic>ANIMAL TESTING ALTERNATIVES</topic><topic>Animals</topic><topic>ANTIINFECTIVE AGENTS</topic><topic>ANTIMICROBIALS</topic><topic>ANTIMICROBIANO</topic><topic>ANTIMICROBIEN</topic><topic>Atlantic Ocean</topic><topic>Biological and medical sciences</topic><topic>CELL CULTURE</topic><topic>Cells, Cultured</topic><topic>CHO Cells - drug effects</topic><topic>Cricetinae</topic><topic>CULTIVO DE CELULAS</topic><topic>CULTURE DE CELLULE</topic><topic>CYTOTOXICITY</topic><topic>EXTRACTOS</topic><topic>EXTRACTS</topic><topic>EXTRAIT</topic><topic>Marine</topic><topic>Marine Toxins - toxicity</topic><topic>Medical sciences</topic><topic>NEW JERSEY</topic><topic>NEW YORK</topic><topic>NUEVA YORK</topic><topic>PHAEOPHYCEAE</topic><topic>PHAEOPHYTA</topic><topic>Plant poisons toxicology</topic><topic>TOXICIDAD</topic><topic>TOXICITE</topic><topic>TOXICITY</topic><topic>Toxicology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dilorenzo, A.M</creatorcontrib><creatorcontrib>Lustigman, B</creatorcontrib><creatorcontrib>Correa, M</creatorcontrib><creatorcontrib>Aglione, A</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Environment Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Environment Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Engineering Research Database</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 1: Biological Sciences & Living Resources</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>ASFA: Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Marine Biotechnology Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Bulletin of environmental contamination and toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dilorenzo, A.M</au><au>Lustigman, B</au><au>Correa, M</au><au>Aglione, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of algae extracts from New York/New Jersey coastline, USA on cultured mammalian cells</atitle><jtitle>Bulletin of environmental contamination and toxicology</jtitle><addtitle>Bull Environ Contam Toxicol</addtitle><date>1993-09-01</date><risdate>1993</risdate><volume>51</volume><issue>3</issue><spage>367</spage><epage>373</epage><pages>367-373</pages><issn>0007-4861</issn><eissn>1432-0800</eissn><coden>BECTA6</coden><abstract>The toxicity of antimicrobial extracts of the algae Fucus spiralis and Fucus vesiculosus was determined by an in-vitro technique on cultured Chinese Hamster Ovary cells as an alternative to animal testing. The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plating efficiency of the cells were used as markers. F. spirilis showed less toxicity as determined by greater plating efficiency and ability to move by mitosis into areas free of attached cells than F. vesiculosis.</abstract><cop>New York, NY</cop><pub>Springer-Verlag</pub><pmid>8219591</pmid><doi>10.1007/BF00201754</doi><tpages>7</tpages></addata></record> |
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| ispartof | Bulletin of environmental contamination and toxicology, 1993-09, Vol.51 (3), p.367-373 |
| issn | 0007-4861 1432-0800 |
| language | eng |
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| subjects | ALTERNATIVAS A ENSAYOS CON ANIMALES ALTERNATIVE ANIMAL DE LABORATOIRE ANIMAL TESTING ALTERNATIVES Animals ANTIINFECTIVE AGENTS ANTIMICROBIALS ANTIMICROBIANO ANTIMICROBIEN Atlantic Ocean Biological and medical sciences CELL CULTURE Cells, Cultured CHO Cells - drug effects Cricetinae CULTIVO DE CELULAS CULTURE DE CELLULE CYTOTOXICITY EXTRACTOS EXTRACTS EXTRAIT Marine Marine Toxins - toxicity Medical sciences NEW JERSEY NEW YORK NUEVA YORK PHAEOPHYCEAE PHAEOPHYTA Plant poisons toxicology TOXICIDAD TOXICITE TOXICITY Toxicology |
| title | Effects of algae extracts from New York/New Jersey coastline, USA on cultured mammalian cells |
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