Effects of algae extracts from New York/New Jersey coastline, USA on cultured mammalian cells

The toxicity of antimicrobial extracts of the algae Fucus spiralis and Fucus vesiculosus was determined by an in-vitro technique on cultured Chinese Hamster Ovary cells as an alternative to animal testing. The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plat...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of environmental contamination and toxicology 1993-09, Vol.51 (3), p.367-373
Hauptverfasser:	Dilorenzo, A.M, Lustigman, B, Correa, M, Aglione, A
Format:	Artikel
Sprache:	eng
Schlagworte:	ALTERNATIVAS A ENSAYOS CON ANIMALES ALTERNATIVE ANIMAL DE LABORATOIRE ANIMAL TESTING ALTERNATIVES Animals ANTIINFECTIVE AGENTS ANTIMICROBIALS ANTIMICROBIANO ANTIMICROBIEN Atlantic Ocean Biological and medical sciences CELL CULTURE Cells, Cultured CHO Cells - drug effects Cricetinae CULTIVO DE CELULAS CULTURE DE CELLULE CYTOTOXICITY EXTRACTOS EXTRACTS EXTRAIT Marine Marine Toxins - toxicity Medical sciences NEW JERSEY NEW YORK NUEVA YORK PHAEOPHYCEAE PHAEOPHYTA Plant poisons toxicology TOXICIDAD TOXICITE TOXICITY Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The toxicity of antimicrobial extracts of the algae Fucus spiralis and Fucus vesiculosus was determined by an in-vitro technique on cultured Chinese Hamster Ovary cells as an alternative to animal testing. The recovery of mitosis/locomotion after monolayer scraping of confluent cultures and the plating efficiency of the cells were used as markers. F. spirilis showed less toxicity as determined by greater plating efficiency and ability to move by mitosis into areas free of attached cells than F. vesiculosis.
ISSN:	0007-4861 1432-0800
DOI:	10.1007/BF00201754