Vibrindole A, a Metabolite of the Marine Bacterium, Vibrio parahaemolyticus, Isolated from the Toxic Mucus of the Boxfish Ostracion cubicus

The EtOAc extract of the whole culture medium of Vibrio parahaemolyticus, which inhabits the toxic mucus of the box fish Ostracion cubicus, afforded a new indole-derived natural product, vibrindole A [1], along with some known cyclic dipeptides and indoles. The structure of 1 was determined by analy...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 1994-11, Vol.57 (11), p.1587-1590
Hauptverfasser:	Bell, Ronit, Carmeli, Shmuel, Sar, Nehemia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - chemistry Bacillus subtilis - drug effects CHEMICAL COMPOSITION COMPOSICION QUIMICA COMPOSITION CHIMIQUE CYTOTOXIC COMPOUNDS ESPECTROMETRIA Ethanol Fish Venoms Fishes - microbiology INDOL INDOLES Indoles - chemistry Indoles - isolation & purification Indoles - pharmacology Magnetic Resonance Spectroscopy Marine MARINE FISHES METABOLITE METABOLITES METABOLITOS Microbial Sensitivity Tests MOLECULAR CONFORMATION Molecular Structure Mucous Membrane - microbiology PECES MARINOS PEPTIDE PEPTIDES PEPTIDOS PHARMACEUTICAL PRODUCTS POISSON DE MER SALTWATER FISHES SPECTRAL ANALYSIS SPECTROMETRIE SPECTROMETRY Staphylococcus - drug effects Staphylococcus aureus - drug effects SUBSTANCE TOXIQUE SUSTANCIAS TOXICAS TOXIC SUBSTANCES VIBRIO Vibrio parahaemolyticus Vibrio parahaemolyticus - chemistry Vibrio parahaemolyticus - isolation & purification Vibrio parahaemolyticus - metabolism
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Beschreibung
Zusammenfassung:	The EtOAc extract of the whole culture medium of Vibrio parahaemolyticus, which inhabits the toxic mucus of the box fish Ostracion cubicus, afforded a new indole-derived natural product, vibrindole A [1], along with some known cyclic dipeptides and indoles. The structure of 1 was determined by analysis of its physicochemical characteristics.
ISSN:	0163-3864 1520-6025
DOI:	10.1021/np50113a022